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Glycotoxin is one of the major poisons in the Creatures series. It works by depleting glycogen, which is a long-term energy store for creatures. In C2 and C3/DS, Glycotoxin can be countered by Arnica, but in C1, there is nothing for it but to feed your norn and hope it can digest the food quickly enough to regain its life force.
Sources of glycotoxin include the Deathcap Mushroom in C1 and C2, and bacteria and detritus in C3/DS.
In C3/DS, it damages the Liver Anabolic organ and may cause creatures to shiver, as the breakdown of glycotoxin produces coldness as a side-product.